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1

Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study

Canuso, Carla M., Singh, Jaskaran B., Fedgchin, Maggie, Alphs, Larry, Lane, Rosanne, Lim, Pilar, Pinter, Christine, Hough, David, Sanacora, Gerard, Manji, Husseini, Drevets, Wayne C.

Journal:

Year:

2019

Language:

english

File:

PDF, 910 KB

english, 2019

2

The InterSePT scale for suicidal thinking reliability and validity

J.P Lindenmayer, Pal Czobor, Larry Alphs, Ann-Marie Nathan, Ravi Anand, Zahur Islam, James C.Y Chou

Journal:

Schizophrenia Research

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

3

Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial

Larry Alphs, Cynthia A Bossie, Jennifer K Sliwa, Yi-Wen Ma, Norris Turner

Journal:

Annals of General Psychiatry

Year:

2011

Language:

english

File:

PDF, 320 KB

english, 2011

4

The Concept of Supersensitivity Psychosis

KIRKPATRICK, BRIAN, ALPHS, LARRY, BUCHANAN, ROBERT W.

Journal:

Journal of Nervous & Mental Disease

Year:

1992

File:

PDF, 714 KB

1992

5

Validation of the 16-item negative symptom assessment

Bradley N. Axelrod, Robert S. Goldman, Larry D. Alphs

Journal:

Journal of Psychiatric Research

Year:

1993

Language:

english

File:

PDF, 439 KB

english, 1993

6

Predicting suicidal risk in schizophrenic and schizoaffective patients in a prospective two-year trial

Steven G Potkin, Larry Alphs, Chuanchieh Hsu, K Ranga Rama Krishnan, Ravi Anand, Frederick K Young, Herbert Meltzer, Alan Green

Journal:

Biological Psychiatry

Year:

2003

Language:

english

File:

PDF, 74 KB

english, 2003

7

Dosing and Switching Strategies for Paliperidone Palmitate

Samtani, Mahesh N., Gopal, Srihari, Gassmann-Mayer, Cristiana, Alphs, Larry, Palumbo, Joseph M.

Journal:

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

8

Issues and perspectives in designing clinical trials for negative symptoms in schizophrenia

Marder, Stephen R., Alphs, Larry, Anghelescu, Ion-George, Arango, Celso, Barnes, Thomas R.E., Caers, Ivo, Daniel, David G., Dunayevich, Eduardo, Fleischhacker, W. Wolfgang, Garibaldi, George, Green, M

Journal:

Schizophrenia Research

Year:

2013

Language:

english

File:

PDF, 273 KB

english, 2013

9

Fatigue across the CNS spectrum: a clinical review

Targum, Steven D., Fava, Maurizio, Alphs, Larry D., Lynn Starr, H., Wessel, Thomas C., Hilt, Dana C.

Journal:

Fatigue: Biomedicine, Health & Behavior

Year:

2014

Language:

english

File:

PDF, 169 KB

english, 2014

10

Patients’ Preferences Related to Benefits, Risks, and Formulations of Schizophrenia Treatment

Levitan, Bennett, Markowitz, Michael, Mohamed, Ateesha F., Johnson, F. Reed, Alphs, Larry, Citrome, Leslie, Bridges, John F. P.

Journal:

Psychiatric Services

Year:

2015

Language:

english

File:

PDF, 576 KB

english, 2015

11

Effect of Clozapine on Psychogenic Polydipsia in Chronic Schizophrenia

LEE, HONG SHICK, KWON, KONG YOUNG, ALPHS, LARRY D., MELTZER, HERBERT Y.

Journal:

Journal of Clinical Psychopharmacology

Year:

1991

File:

PDF, 198 KB

1991

12

Suicidality and Risk of Suicide—Definition, Drug Safety Concerns, and a Necessary Target for Drug Development

Meyer, Roger E., Salzman, Carl, Youngstrom, Eric A., Clayton, Paula J., Goodwin, Frederick K., Mann, J. John, Alphs, Larry D., Broich, Karl, Goodman, Wayne K., Greden, John F., Meltzer, Herbert Y., No

Journal:

The Journal of Clinical Psychiatry

Year:

2010

Language:

english

File:

PDF, 579 KB

english, 2010

13

Patient Report with the Suicide Ideation and Behavior Assessment Tool (SIBAT): Acceptability and Sensitivity to Rapid Change

Williamson, David, Canuso, Carla, Fu, Dong-Jing, Lane, Roseanne, May, Roberta, Bossaller, Nicholas, Shelton, Richard, Alphs, Larry

Journal:

Biological Psychiatry

Year:

2017

Language:

english

File:

PDF, 43 KB

english, 2017

14

PERSEVERE: A Study of Esketamine for the Reduction of the Symptoms of Major Depressive Disorder, including Suicidal Ideation, in Subjects Assessed to Be at Imminent Risk for Suicide

Canuso, Carla, Singh, Jaskaran, Fedgchin, Maggie, Alphs, Larry, Lane, Roseanne, Lim, Pilar, Pinter, Christine, Manji, Husseini, Drevets, Wayne

Journal:

Biological Psychiatry

Year:

2017

Language:

english

File:

PDF, 42 KB

english, 2017

15

Comparison of long-acting and oral antipsychotic treatment effects in patients with schizophrenia, comorbid substance abuse, and a history of recent incarceration: An exploratory analysis of the PRIDE study

Lynn Starr, H., Bermak, Jason, Mao, Lian, Rodriguez, Steve, Alphs, Larry

Journal:

Schizophrenia Research

Year:

2017

Language:

english

File:

PDF, 778 KB

english, 2017

16

518. Patient and Clinician Acceptance of the Suicide Ideation and Behavior Assessment Tool (SIBAT)

Alphs, Larry, Fu, Dong-Jing, Canuso, Carla

Journal:

Biological Psychiatry

Year:

2017

Language:

english

File:

PDF, 60 KB

english, 2017

17

A quantitative systems pharmacology study on optimal scenarios for switching to paliperidone palmitate once-monthly

Geerts, Hugo, Spiros, Athan, Roberts, Patrick, Alphs, Larry

Journal:

Schizophrenia Research

Year:

2018

Language:

english

File:

PDF, 668 KB

english, 2018

18

Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study

Canuso, Carla M., Singh, Jaskaran B., Fedgchin, Maggie, Alphs, Larry, Lane, Rosanne, Lim, Pilar, Pinter, Christine, Hough, David, Sanacora, Gerard, Manji, Husseini, Drevets, Wayne C.

Journal:

American Journal of Psychiatry

Year:

2018

Language:

english

File:

PDF, 769 KB

english, 2018

19

Projecting the Potential Effect of Using Paliperidone Palmitate Once-Monthly and Once-Every-3-Months Long-Acting Injections Among Medicaid Beneficiaries with Schizophrenia

Basu, Anirban, Benson, Carmela, Alphs, Larry

Journal:

Journal of Managed Care & Specialty Pharmacy

Year:

2018

Language:

english

File:

PDF, 255 KB

english, 2018

20

156 Improvement in Disease Severity in Patients With Treatment-Resistant Depression Following Treatment With Intranasal Esketamine

Nash, Abigail, Shawi, May, Singh, Jaskaran, Daly, Ella, Copper, Kimberly, Lim, Pilar, Lane, Rosanne, Gogate, Jagadish, DiBernardo, Allitia, Hough, David, Alphs, Larry

Journal:

Year:

2018

Language:

english

File:

PDF, 81 KB

english, 2018

21

Economic Burden of Treatment-Resistant Depression Among Patients Hospitalized for Major Depressive Disorder in the United States

Lin, Jay, Szukis, Holly, Sheehan, John J., Alphs, Larry, Menges, Brandy, Lingohr-Smith, Melissa, Benson, Carmela

Journal:

Psychiatric Research and Clinical Practice

Year:

2019

Language:

english

File:

PDF, 547 KB

english, 2019

22

Suicide Ideation and Behavior Assessment Tool (SIBAT): Evaluation of Intra- and Inter-Rater Reliability, Validity, and Mapping to Columbia Classification Algorithm of Suicide Assessment

Alphs, Larry, Fu, Dong-Jing, Williamson, David, Turkoz, Ibrahim, Jamieson, Carol, Revicki, Dennis, Canuso, Carla M.

Journal:

Psychiatry Research

Year:

2020

File:

PDF, 68 KB

2020

23

Validation of a 4-item Negative Symptom Assessment (NSA-4): a short, practical clinical tool for the assessment of negative symptoms in schizophrenia

Larry Alphs, Robert Morlock, Cheryl Coon, Pilar Cazorla, Armin Szegedi, John Panagides

Journal:

International Journal of Methods in Psychiatric Research

Year:

2011

Language:

english

File:

PDF, 141 KB

english, 2011

24

Adjunctive long-acting risperidone in patients with bipolar disorder who relapse frequently and have active mood symptoms

Wayne Macfadden, Caleb M Adler, Ibrahim Turkoz, John T Haskins, Norris Turner, Larry Alphs

Journal:

Year:

2011

Language:

english

File:

PDF, 178 KB

english, 2011

25

Onset of efficacy and tolerability following the initiation dosing of long-acting paliperidone palmitate: post-hoc analyses of a randomized, double-blind clinical trial

Cynthia A Bossie, Jennifer K Sliwa, Yi-Wen Ma, Dong-Jing Fu, Larry Alphs

Journal:

Year:

2011

Language:

english

File:

PDF, 612 KB

english, 2011

26

A case study comparing a randomized withdrawal trial and a double-blind long-term trial for assessing the long-term efficacy of an antidepressant

Craig Mallinckrodt, Christy Chuang-Stein, Paul McSorley, Jeffrey Schwartz, Donald G. Archibald, David G. Perahia, Michael J. Detke, Larry Alphs

Journal:

Pharmaceutical Statistics

Year:

2007

Language:

english

File:

PDF, 248 KB

english, 2007

27

Development of the Clozaril Patient Management System

Bijan Bastani, Larry D. Alphs, Herbert Y. Meltzer

Journal:

Psychopharmacology

Year:

1989

Language:

english

File:

PDF, 438 KB

english, 1989

28

A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states

Roger S McIntyre, Miriam Cohen, Jun Zhao, Larry Alphs, Thomas A Macek, John Panagides

Journal:

Bipolar Disorders

Year:

2009

Language:

english

File:

PDF, 322 KB

english, 2009

29

Asenapine versus olanzapine in acute mania: a double-blind extension study

Roger S McIntyre, Miriam Cohen, Jun Zhao, Larry Alphs, Thomas A Macek, John Panagides

Journal:

Bipolar Disorders

Year:

2009

Language:

english

File:

PDF, 298 KB

english, 2009

30

A randomized, double-blind, placebo-controlled study of maintenance treatment with adjunctive risperidone long-acting therapy in patients with bipolar I disorder who relapse frequently

Wayne Macfadden, Larry Alphs, J Thomas Haskins, Norris Turner, Ibrahim Turkoz, Cynthia Bossie, Mary Kujawa, Ramy Mahmoud

Journal:

Bipolar Disorders

Year:

2009

Language:

english

File:

PDF, 379 KB

english, 2009

31

Asenapine in the treatment of acute mania in bipolar I disorder: A randomized, double-blind, placebo-controlled trial

Roger S. McIntyre, Miriam Cohen, Jun Zhao, Larry Alphs, Thomas A. Macek, John Panagides

Journal:

Journal of Affective Disorders

Year:

2010

Language:

english

File:

PDF, 515 KB

english, 2010

32

Asenapine for long-term treatment of bipolar disorder: A double-blind 40-week extension study

Roger S. McIntyre, Miriam Cohen, Jun Zhao, Larry Alphs, Thomas A. Macek, John Panagides

Journal:

Journal of Affective Disorders

Year:

2010

Language:

english

File:

PDF, 317 KB

english, 2010

33

Association between changes on the Negative Symptom Assessment scale (NSA-16) and measures of functional outcome in schizophrenia

Dawn I. Velligan, Larry Alphs, Scott Lancaster, Robert Morlock, Jim Mintz

Journal:

Psychiatry Research

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

34

Clozapine and sudden death

Barbara Warner, Larry Alphs, Juerg Schaedelin, Thomas Koestler

Journal:

Year:

2000

Language:

english

File:

PDF, 42 KB

english, 2000

35

The schedule for the deficit syndrome: An instrument for research in schizophrenia

Brian Kirkpatrick, Robert W. Buchanan, Patricia D. McKenny, Larry D. Alphs, William T. Carpenter Jr.

Journal:

Psychiatry Research

Year:

1989

Language:

english

File:

PDF, 360 KB

english, 1989

36

Labile hypertension after antipsychotic drug withdrawal: A case report

Gunvant K. Thaker, Larry Alphs, Carol A. Tamminga

Journal:

Biological Psychiatry

Year:

1985

Language:

english

File:

PDF, 199 KB

english, 1985

37

A circadian rhythm in dark induction of rat pineal serotonin: coenzyme a:N-acetyltransferase activity

Larry Alphs, Alfred Heller

Journal:

Year:

1978

Language:

english

File:

PDF, 181 KB

english, 1978

38

Isometric force control in schizophrenic patients with tardive dyskinesia

P.Bart Vrtunski, Larry D. Alphs, Herbert Y. Meltzer

Journal:

Psychiatry Research

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

39

Disengagement of attention in chronic schizophrenia

Milton E. Strauss, Larry Alphs, John Boekamp

Journal:

Psychiatry Research

Year:

1992

Language:

english

File:

PDF, 475 KB

english, 1992

40

Factor structure of the negative symptom assessment

Bradley N. Axelrod, Robert S. Goldman, John L. Woodard, Larry D. Alphs

Journal:

Psychiatry Research

Year:

1994

Language:

english

File:

PDF, 455 KB

english, 1994

41

Motor mechanisms in schizophrenic patients with tardive dyskinesia

P.Bart Vrtunski, Larry D. Alphs, Herbert Y. Meltzer

Journal:

Psychiatry Research

Year:

1994

Language:

english

File:

PDF, 1.19 MB

english, 1994

42

Effects of acute paliperidone palmitate treatment in subjects with schizophrenia recently treated with oral risperidone

Jennifer Kern Sliwa, Cynthia A. Bossie, Yi-Wen Ma, Larry Alphs

Journal:

Schizophrenia Research

Year:

2011

Language:

english

File:

PDF, 408 KB

english, 2011

43

Neurocognitive performance does not correlate with suicidality in schizophrenic and schizoaffective patients at risk for suicide

Steven G Potkin, Ravi Anand, Larry Alphs, Kirsten Fleming

Journal:

Schizophrenia Research

Year:

2003

Language:

english

File:

PDF, 105 KB

english, 2003

44

CORRELATING FUNCTIONAL DOMAINS AND SYMPTOM CLUSTERS IN SCHIZOPHRENIA

Larry Alphs, Wayne Macfadden, Tom Haskins, Cynthia Bossie, Young Zhu, Bruce Simonson

Journal:

Schizophrenia Research

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

45

HISTORICAL PERSPECTIVE ON DRUG-PLACEBO DIFFERENCES: IMPLICATIONS FOR GENERALIZABILITY OF RESULTS AND FUTURE TRIAL DESIGN

Journal:

Schizophrenia Research

Year:

2008

Language:

english

File:

PDF, 62 KB

english, 2008

46

JANSSEN

Journal:

Schizophrenia Research

Year:

2012

Language:

english

File:

PDF, 65 KB

english, 2012

47

Poster #188 MAINTENANCE TREATMENT WITH RISPERIDONE LONG-ACTING INJECTION VS PLACEBO IN SUBJECTS RECENTLY DIAGNOSED WITH BIPOLAR DISORDER: A SUBGROUP ANALYSIS

Larry Alphs, Dong-Jing Fu, Jennifer Kern Sliwa, Yi-Wen Ma, Cynthia A. Bossie

Journal:

Schizophrenia Research

Year:

2012

Language:

english

File:

PDF, 91 KB

english, 2012

48

Poster #187 EVALUATING INJECTION SITE PAIN WITH LONG-ACTING ATYPICAL ANTIPSYCHOTICS USING CLINICAL TRIAL DATABASES OF SUBJECTS WITH SCHIZOPHRENIA

Jennifer Kern Sliwa, Srihari Gopal, Dong-Jing Fu, Isaac Nuamah, Larry Alphs

Journal:

Schizophrenia Research

Year:

2012

Language:

english

File:

PDF, 69 KB

english, 2012

49

Poster #185 REMISSION WITH CONTINUED PALIPERIDONE PALMITATE TREATMENT IN STABLE SUBJECTS WITH SCHIZOPHRENIA

loseph Hulihan, Cynthia A. Bossie, Dong-Jing Fu, Jennifer Kern Sliwa, Yi-Wen Ma, Larry D. Alphs

Journal:

Schizophrenia Research

Year:

2012

Language:

english

File:

PDF, 67 KB

english, 2012

50

Poster #199 RATES AND TIME COURSE OF EXTRAPYRAMIDAL SYMPTOMS: A COMPARISON OF ORAL AND LONG-ACTING INTRAMUSCULAR (LAI) PALIPERIDONE RANDOMIZED CONTROLLED STUDIES

Srihari Gopal, Yanning Liu, Larry Alphs, Adam Savitz, Isaac Nuamah, David Hough

Journal:

Schizophrenia Research

Year:

2012

Language:

english

File:

PDF, 70 KB

english, 2012